- Ear & Body Piercing, Souderton
- Eastern Orthodox Church, Souderton
- Education, Souderton
- Education & Information Services, Souderton
- Educational & School Supplies & Equipment, Souderton - Classroom & Teacher Supply Stores
- Educational Program Administration, Souderton
- Electric Companies, Souderton
- Electrical Control Systems & Materials, Souderton
- Electrical Supplies, Parts & Equipment, Souderton - Wholesale & Manufacturers
- Electricians, Souderton - Electrical Contractors
- Electronic Repair Shops , Souderton
- Electronic Research, Design & Development, Souderton
- Electronics Repair & Maintenance , Souderton
- Electronics Stores, Souderton
- Elementary Schools, Souderton
- Embroidery, Souderton
- Emergency Notification Services, Souderton
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- Emergency Services, Souderton
- Emissions Testing, Souderton - Smog Check
- Employee Benefit Plan Consulting Services, Souderton
- Employment Agencies, Souderton - Staffing Agencies
- Energy & Conservation Agencies, Souderton
- Engine Rebuild, Repair & Exchange, Souderton
- Engineer & Architect Services, Souderton - Engineering & Architecture Service
- Engineering Consultants, Souderton - Consulting Engineers
- Entertainment & Recreation, Souderton
- Environmental Consultants, Souderton - Ecological Consulting
- European Cuisine, Souderton
- Evangelical Church, Souderton
- Excavation Contractors, Souderton - Excavating - Excavator Companies
- Exercise Equipment Repair & Service, Souderton
- Exercise Equipment Stores, Souderton - Fitness & Gym Equipment
- Export Services, Souderton
- Exporters, Souderton
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