- Safe & Vault, Newville
- Safety & Security Systems & Consultants, Newville
- Salvage Yards, Junk Yards & Wrecker Service, Newville
- Screen Printing, Newville
- Sealcoating, Newville - Asphalt Sealcoating & Paving
- Secondary Schools, Newville
- Security Guard & Patrol Service, Newville - Bodyguard, Guard Dogs, Etc
- Security Investigative Services, Newville
- Security Services, Newville
- Senior Citizens Service & Health Organizations, Newville
- Septic Tank Installation & Repair, Newville - Septic Systems
- Septic Tank Pumping & Cleaning, Newville - Septic Systems
- Septic Tanks & Septic Systems Contractors, Newville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Service Establishment Supplies & Equipment, Newville
- Sewage Plant Operation, Newville
- Sewer & Drain Cleaning & Repair, Newville - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Newville
- Sewing Machine Repair & Service, Newville
- Sewing Machines, Equipment & Supplies, Newville
- Sewing Ribbons, Newville
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- Sharpening Service, Newville
- Shopping & Shopping Services, Newville
- Small Appliances, Newville
- Snow Removal Services, Newville - Snow Plow Service
- Social Services & Welfare, Newville
- Societies & Foundation Associations, Newville
- Special Dies Tools Jigs & Fixtures Manufacturers, Newville
- Speciality Food Stores, Newville
- Specialty Animal Services, Newville
- Specialty Stores, Newville
- Sports Teams & Franchises, Newville
- Sprinkler Alarm Systems, Newville - Fire Sprinkler Systems
- Staffing & Support Services, Newville
- State Government, Newville
- Steam Cleaner - Commercial & Industrial, Newville - Steam Cleaning - Upholstery, Floor, Carpet, etc
- Steel & Metal Goods, Newville - Steel Distributors
- Storage Containers, Newville
- Surveying Engineer, Newville
- Surveyor Services, Newville - Surveying Service
- Sweepers & Scrubbers Industrial, Newville - Sweeping Service
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