- Sandwich Shop Restaurants, Millersville
- Savings & Loans Institutions, Millersville
- Savings Banks, Millersville
- Screen Printing, Millersville
- Secondary Schools, Millersville
- Security Brokers & Dealers, Millersville
- Senior Citizens Service & Health Organizations, Millersville
- Sewer & Drain Cleaning & Repair, Millersville - Drain Cleaner & Installation Services
- Sewer Construction Contractors, Millersville - Sewer Line, Pipe Installation & Repair Services
- Shoe Repair Shops, Millersville
- Shoe Stores, Millersville - Mens, Womens & Kids Shoes
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- Shopping & Shopping Services, Millersville
- Sign Hanging & Installation Service, Millersville - Signs Erectors & Hangers
- Snow Removal Services, Millersville - Snow Plow Service
- Social Services & Welfare, Millersville
- Societies & Foundation Associations, Millersville
- Special Interest Schools Or Instruction, Millersville
- Specialty Stores, Millersville
- Stocks & Bond Brokers, Millersville
- Student Dormitories, Millersville
- Swimming Pools, Millersville
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