- Sandwich Shop Restaurants, Frackville
- Sanitation Consultants, Frackville
- Savings Banks, Frackville
- Security & Surveillance System & Equipment, Frackville
- Security Alarm Systems - Home & Business, Frackville
- Security Control Systems & Monitoring, Frackville - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Investigative Services, Frackville
- Security Services, Frackville
- Senior Citizens Service & Health Organizations, Frackville
- Shoe Store - More, Frackville
- Shoe Stores, Frackville - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Frackville
- Small Appliances, Frackville
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- Social Services & Welfare, Frackville
- Societies & Foundation Associations, Frackville
- Southern Style Restaurants, Frackville
- Special Events Photographers, Frackville
- Specialty Stores, Frackville
- Sporting Goods Equipment Rental, Frackville
- Sporting Goods Stores, Frackville
- Sports & Recreational Services, Frackville
- Sportswear Clothing Stores, Frackville - Sports Clothes
- Staffing & Support Services, Frackville
- State Government, Frackville
- Submarine Sandwich Restaurants, Frackville
- Swimming Pools Supplies, Equipment & Accessories, Frackville
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