- Sand Gravel & Aggregate, Annville
- Sandblasting, Annville - General Contractors
- Sandwich Shop Restaurants, Annville
- Satellite TV Service, Annville
- Secondary Schools, Annville
- Secretarial & Court Reporting Services, Annville
- Security Brokers & Dealers, Annville
- Senior Citizens Service & Health Organizations, Annville
- Septic Tanks & Systems, Annville - Wholesale, Dealers & Suppliers
- Sheet Metal Contractors, Annville - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Annville
- Shirts & T-Shirts, Annville
- Shopping & Shopping Services, Annville
- Siding Contractors, Annville - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Snow Removal Equipment Repair & Service, Annville
- Snow Removal Services, Annville - Snow Plow Service
- Social Clubs & Organizations, Annville
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- Social Services & Welfare, Annville
- Societies & Foundation Associations, Annville
- Sound Systems, Microphones & Equipment, Annville
- Special Dies Tools Jigs & Fixtures Manufacturers, Annville
- Special Education & Care, Annville
- Special Events & Party Supply Rental, Annville
- Specialty Animal Services, Annville
- Specialty Stores, Annville
- Specialty Vehicle Rental & Leasing, Annville
- Sporting Goods Equipment Rental, Annville
- Sporting Goods Stores, Annville
- Staffing & Support Services, Annville
- State Government, Annville
- Steak House Restaurants, Annville
- Stocks & Bond Brokers, Annville
- Stove, Oven, Range & Cooktop Parts & Supplies, Annville
- Swimming Pools, Annville
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