- Sandwich Shop Restaurants, West Mifflin
- Satellite & Cable TV Equipment & Systems, West Mifflin
- Satellite Technology & Space Research, West Mifflin
- Savings & Loan Associations, West Mifflin
- Savings Banks, West Mifflin
- Scrap & Waste Materials, West Mifflin
- Seafood Restaurants, West Mifflin
- Secondary Schools, West Mifflin
- Security Alarm Systems - Home & Business, West Mifflin
- Security Brokers & Dealers, West Mifflin
- Security Investigative Services, West Mifflin
- Security Services, West Mifflin
- Senators Elected, West Mifflin
- Sewer & Drain Cleaning & Repair, West Mifflin - Drain Cleaner & Installation Services
- Sewer Companies, West Mifflin
- Shirts & T-Shirts, West Mifflin
- Shoe Store - More, West Mifflin
- Shoe Stores, West Mifflin - Mens, Womens & Kids Shoes
- Shooting & Target Ranges, West Mifflin
- Shopping & Shopping Services, West Mifflin
- Siding Contractors, West Mifflin - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Signs, West Mifflin
- Signs Residential Professional, West Mifflin
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- Small Appliances, West Mifflin
- Snacks & Desserts, West Mifflin
- Snow Removal Services, West Mifflin - Snow Plow Service
- Social Services & Welfare, West Mifflin
- Societies & Foundation Associations, West Mifflin
- Soup & Salad Restaurants, West Mifflin
- Special Interest Schools Or Instruction, West Mifflin
- Specialty Animal Services, West Mifflin
- Specialty Stores, West Mifflin
- Speech & Hearing Specialists, West Mifflin
- Sporting Goods Stores, West Mifflin
- Sportswear Clothing Stores, West Mifflin - Sports Clothes
- Stamp Collecting & Coin Dealers , West Mifflin
- State Administrative Agencies, West Mifflin
- State Government, West Mifflin
- Steak House Restaurants, West Mifflin
- Stone Setting Contractors, West Mifflin
- Storage - Household & Commercial-Full Service, West Mifflin
- Substance Abuse Clinics, West Mifflin - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Swimming Pool, Sauna & Spa Contractors, West Mifflin
- Swimming Pools Contractors, West Mifflin - Install Inground - Above Ground Pools
- Swimming Pools Repair, Service, Supplies, Sale & Installation, West Mifflin
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